MJ Clinical Training

GLP-1 Agonists: Expanding Horizons in Addiction Treatment

GLP-1 receptor agonists are not just making waves in weight management and diabetes care—they’re showing potential in addressing various forms of addiction. By modulating dopamine pathways in the brain, these medications could help reduce cravings and compulsive behaviours across a spectrum of addictions.

Current research and potential applications include:

  • Alcohol Use Disorder (AUD): Reduced alcohol cravings and intake in both animal studies and human trials.
  • Nicotine Addiction: Early studies suggest GLP-1s might curb nicotine dependence by dampening reward responses to smoking.
  • Opioid Use Disorder: There’s ongoing exploration into how GLP-1s might help reduce opioid cravings, with promising preclinical results.
  • Binge Eating and Shopping: Anecdotally, some patients report less compulsive eating and even reduced impulsive spending.

These developments point to a broader therapeutic role for GLP-1s, offering hope for tackling addiction alongside obesity.

As a medical weight loss clinician and a medical weight loss training company owner it’s good to see that research is helping us understand the mechanisms of action of these drugs further.

However, coming up to Christmas, will this mean that some people will be getting less presents this year?